Research

IMGENEX INDIA has a strong research program through in-house R&D as well as collaborations with public and private institutions. Areas of biological interest at IMGENEX INDIA include cancer, apoptosis (programmed cell death), molecular signaling pathways, cellular aging, metabolic disorder, neuro-degenerative, genetic and infectious diseases.

The following projects have been funded by DBT & other granting agencies.

• Nanotechnology based peptide therapy for osteoporosis. This project is jointly funded by IMGENEX INDIA and DBT under SBIRI scheme and in collaboration with Institute of Life Sciences, Bhubaneshwar.
• Generation of induced pluripotent stem (iPS) cells from adult somatic cells using non-genomic protein transduction method. This project is also jointly funded by IMGENEX INDIA and DBT under SBIRI scheme.
• Phytochemical analysis and screening of anticancer compound from selected medicinal plants species. This project was carried out in collaboration with Regional Plant Resource Center, Bhubaneshwar and funded by National Medicinal Plants Boards (NMPB), Ministry of Health and Family Welfare, Government of India.
• Studies on Toll Like Receptor (TLR) Response in T Cells funded by Department of Biotechnology, New Delhi and in collaboration with National Institute of Science Education and Research (NISER), Bhubaneshwar.
• Study on IronIII (salen) and IronIII (porphyrin) complexes as anti-tumor metallodrugs. This project is also funded by Department of Biotechnology, New Delhi and in collaboration with National Institute of Science Education and Research (NISER), Bhubaneshwar.
• A joint project with All India Institute of Medical Sciences (AIIMS), New Delhi and York University, Toronto, Canada and Xphase Pharmaceuticals Inc., Toronto, Canada to develop head and neck cancer markers with an aim to develop diagnostic array.
• Development of High Expression Plasmid vectors for Production of Biosimilar Herceptin and Other Recombinant Proteins and Antibodies funded by Department of Biotechnology under BIPP Scheme.
• Diagnostic kit to detect the mutations in common Indian beta-thalassemia for human. This project was in collaboration with National Institute Immunohematology, Mumbai and funded by Indian Council for Medical Research (ICMR), New Delhi.
• Development of “Bio-Process Development for Production of Biosimilar Trastuzumab-Second Phase” funded by BIRAC, DBT
• Validation of serological diagnostic reagents and kits for plant viruses affecting horticultural crops. This project is funded by BIRAC, DBT, New Delhi and in collaboration with Indian Agricultural Research Institute (IARI), New Delhi.
• "Large Scale Production of SARS-CoV-2/COVID-19 Proteins and Development of Antibodies for Serological Tests." This project is funded by BIRAC, DBT, New Delhi.
• "SARS-CoV2 Spike S1 protein production as a possible vaccine candidate." This project is externally funded.